Several case reports can be compiled into a case series to do what?

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Compiling several case reports into a case series helps generate hypotheses and spot patterns across a small group, which provides the groundwork for planning more rigorous research. By showing plausible signals of benefit or harm and giving insight into feasibility and study design, a case series can form the basis for conducting randomized controlled trials. However, it cannot eliminate bias, cannot prove causality, and cannot replace cohort studies because it lacks a control group and randomization.